Njira yabwino kwambiri ndi iti?
-Chizindikiro cha SARS-Cov-2 matenda
Chifukwa chatsimikizira za Coviid-19, adanenanso za matenda odziwika bwino amaphatikiza kutentha thupi, chifuwa, myulgia kapena kutopa. Komabe zizindikirozi sizowoneka zapadera za Covid-19 chifukwa zizindikirizizi zikufanana ndi za matenda ena omwe kachilombo ka kachilomboka monga chimfine monga matendawa. Pakadali pano, kachilombo kwa ma viles nyukiliya PCR (RT-PCR), CT-PCR), CT-PCR) ndi magawo ena a hematology ndi zida zoyambirira zamankhwala. Ma kits ambiri a labotale apangidwa ndipo amagwiritsidwa ntchito poyesa odekha a covid-19 ndi CDC CDC1, US CDC2ndi makampani ena apadera. Mayeso a IGG / IGM1. Kachilombo ka nyukiliya acid Rt-PCR PRIVE ndiye njira yodziwira yazomwe ikudziwika kuti azindikire Covid-19.
Cholimba®New Coronavlrus (SARS-COV-2) ACHINSx PCR Clay (kudziwika kwa majini atatu)
Komabe kuyesa kwa PCr yeniyeni, kuyang'ana majini a kachilomboka, mwachitsanzo mu mphuno minda, pakamwa, kapena andal swabs, amavutika ndi zofooka zambiri:
1) Kuyesedwa uku kumakhala ndi nthawi yayitali ndikuyamba kugwiritsa ntchito opaleshoni; Nthawi zambiri amatenga maola opitilira 2 mpaka atatu kuti apange zotsatira.
2) Kuyesedwa kwa PCR kumafuna malo ogulitsira, zida zodula komanso matesa ophunzitsidwa bwino kuti agwiritse ntchito.
3) Pali ziwerengero zina zabodza za RT-PCR ya Covid-19. Itha chifukwa cha otsika otsika-cov-2 ma virus omwe ali mu mawonekedwe apamwamba a swab (mwatsopano coronavirus makamaka amapatsirana thirakiti, almonary almoli) ndipo mayeso sangazindikire anthu omwe amadwala, ndipo adachotsa kachilomboka ku matupi awo.
Kafukufuku ndi Lirong Zou et al4adapeza kuti ma virus apamwamba adapezeka pambuyo pa chitsandikiro chambiri pambuyo pa mphuno kuposa mmero ndi ma acid acid acid omwe ali ndi SARS-2 amafanana ndi odwala omwe ali ndi matenda a fuluwenza4ndipo zimawoneka zosiyana ndi zomwe zimawoneka mwa odwala omwe ali ndi ndalama za SARS-Cov-2.
Yang PAN et al5Zitsanzo za SINA (Throat Swabs, Sputum, Mkodzo, ndi wopondaponda kuchokera kwa anthu awiri ku Beat Swab ndi Sputum nthawi zambiri adawonetsa ma virus kuposa Throat swab. Palibe RNA RNA idapezeka mu mkodzo kapena stool zitsanzo kuchokera kwa odwala awiriwa.
Kuyesa kwa PCR kumangopereka zotsatira zabwino pomwe kachilomboka akadalipo. Mayeso sangazindikire anthu omwe amadwala, adachira, ndikuyeretsa kachilomboka m'matupi awo. Modabwitsa, pafupifupi 30% -50% anali ndi chiyembekezo cha PCR mwa odwala cornanavirus chibayo. Zambiri zaposachedwa chibayo odwala sangathe kupezeka chifukwa cha mayeso oyipa a nuclectic acid, kuti sangathe kulandira chithandizo chofanana ndi nthawi. Kuyambira koyamba mpaka kusindikiza kwa zitsogozo zisanu ndi chimodzi, ndikudalira maziko pamalingaliro a matenda a nucleic acid, omwe ali ndi vuto lalikulu ", Dr. Chipatala, ndi chakufa. Pa nthawi ya moyo wake, anali ndi mayeso atatu a acidic acid pankhani ya malungo ndi kutsokomola, ndipo nthawi yotsiriza adapeza zotsatira zabwino za PCR.
Atakambirana ndi akatswiri, adaganiza zowonjezera njira zoyeserera za seramu ngati chitsimikizo chatsopano. Ngakhale kuyesedwa kwa antipody, kutchedwa mayeso otchedwa Servolological mayeso, omwe angatsimikizire ngati wina atadwala ngakhale mthupi lawo chitatha kuchiritsa kachilombo komwe kamayambitsa covid-19.
Amphamvu amphamvu® SARS-COV-2 igg / igm antibody kuyesa mwachangu
Kuyesa kwa ntchito ya IGG / igm kumathandizira kuti tisanthule anthu ambiri omwe adadwala, chifukwa milandu yambiri imawoneka kuti ikufalikira kuchokera kwa odwala a Asystermatic omwe sangazindikiridwe mosavuta. Banja ku Singapore, mwamunayo anayesedwa ndi PCR, zotsatira za makina ake a PCr zinali zoipa, koma zotsatira za ntchito ya antibody zidawonetsa kuti anali ndi ma antibodies, monga adachitira mwamunayo.
Malingaliro a Serlogical, ayenera kuvomerezedwa mosamala kuti atsimikizire kuti amathandizidwa, koma okha a ma antibodies okha otsutsana ndi kachilomboka. Chodetsa nkhawa china chinali chakuti kufanana pakati pa ma virus komwe kumapangitsa kuti matenda amphamvu kwambiri a syndrome ndi Covid-19 atha kubweretsa kudutsa. The igg-igg yopangidwa ndi xue feng Wang6idawerengedwa kuti imatha kugwiritsidwa ntchito ngati mayeso osamalira bwino (poct), chifukwa imatha kuchitidwa pafupi ndi bedi ndi magazi a chala. Kukomera kuli ndi chidwi cha 88.66% ndi mawonekedwe a 90.63%. Komabe, panali zotsatira zabwino komanso zabodza.
Mu mtundu wosinthidwa wa China ku China1, milandu yotsimikizika imafotokozedwa kuti nditaikira ngati milandu yomwe imakumana ndi ina iliyonse yotsatirayi:
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(2) Kusakanikirana kwa ma virus ku ma virus kuchokera pakupuma, magazi kapena ma stool zitsanzo ndizosangalatsa kwambiri ndi omwe amadziwika ndi a SARS-Cov-2;
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Kuzindikira ndi Chithandizo cha Covid-19
| Kachitidwe kazinthu | Odudwa | Zinatsimikizira kusintha kwa diastiastia |
| Mtundu wa 7 | Amarmar.2020 | ❶ PCR ❷ ngs ❸ igm + igg |
| Mtundu wa 6th | 18 Feb.2020 | ❶ PCR ❷ ngs |
Kuchulidwa
1.
http://www.nhc.gov.cn/yzygj/s752m/003/a3114b98b98
2. Kafukufuku amagwiritsa ntchito PC-PCR Protocol ya RT-PCR yodziwika ya 2019-NCOV
https://www.cdc.gov/coronavirus/coronavirus19-ncov/lab/rt-pcr-Detherdets.htt
3. Singapore akuti amagwiritsa ntchito mayeso a antibody kuti muwone matenda a coronavirus
https://www.sciencemag.org/news/2020/02/singapore-claims-first-use-antibody-test-track-coronavirus-infections
4.Sars-Cov-2 Cirral Cleirmiration zonena za kupuma kwa odwala omwe ali ndi zaka 19,2020 doi: 10,2056 / nejmc2001737
5.Viralloads a SARS-COV-2 muzochitika za Malonda a Lantert Diste 2022 2111333
6. Kukula kwa matenda a igm-igg ophatikizira mayeso a antibody kwa SARS-COV-2
Kuzindikira Kuzindikira Xuefang Wang Orcid ID: 0000-0001-8854-275X
Post Nthawi: Mar-17-2020
