MAU OYAMBA
HSV ndi envelopu, DNA-wokhala kachilombo morphologically ofanana ndi enamamembala a mtundu Herpesviridae.Awiri antigenically osiyana ndiodziwika, osankhidwa amtundu 1 ndi mtundu wa 2.

HSV mtundu 1 ndi 2 nthawi zambiri amakhudzidwa ndi matenda apakamwapatsekeke, khungu, diso ndi maliseche, Matenda a chapakati manthameningoencephalitis (meningoencephalitis) ndi matenda oopsa kwambiri mwa mwana wakhandaodwala immunocompromised amawonedwanso, ngakhale kawirikawiri.Pambuyo pachachikulu matenda kuthetsedwa, kachilombo angakhalepo mu mawonekedwe zobisika mu manthaminofu, pomwe imatha kuyambiranso, pansi pazifukwa zina, kuyambitsa akuyambiranso kwa zizindikirozo.

Kuwonetsedwa kwachipatala kwa genital herpes kumayamba kufalikirama macules ndi ma papules opweteka angapo, omwe amakhwima kukhala masango omveka bwino,ma vesicles odzaza madzimadzi ndi ma pustules.Ma vesicles amang'ambika ndikupanga zilonda.Khunguzilonda kutumphuka, pamene zotupa pa mucous nembanemba amachira popanda kutumphuka.Muakazi, zilonda zimachitika pa introitus, labia, perineum, kapena perianal dera.Amunanthawi zambiri amakhala ndi zotupa pa shaft kapena glans.Wodwala nthawi zambiri amakulamatenda inguinal adenopathy.Matenda a perianal amapezekanso mu MSM.Pharyngitis imatha kuchitika ndi kukhudzana mkamwa.

Kafukufuku wa serology akusonyeza kuti anthu 50 miliyoni ku United States ali ndi malisecheMatenda a HSV.Ku Europe, HSV-2 imapezeka mu 8-15% ya anthu wamba.MuAfrica, ziwopsezo zakufalikira ndi 40-50% mwa azaka za 20.HSV ndiye akutsogolerachifukwa cha zilonda zakumaliseche.Matenda a HSV-2 amachulukitsa mwayi wogonanakutenga kachilombo ka HIV (HIV) komanso kumawonjezekakufala.

Mpaka posachedwapa, mavairasi kudzipatula mu selo chikhalidwe ndi mtima wa mtundu wa HSVndi utoto wa fulorosenti wakhala chinsinsi cha kuyezetsa nsungu kwa odwalakuwonetsa zilonda zakumaliseche.Kupatula kuyesa kwa PCR kwa HSV DNAzasonyezedwa kukhala tcheru kwambiri kuposa mavairasi chikhalidwe ndipo ali mwachindunji kutikuposa 99.9%.Koma njira izi m'machitidwe azachipatala pano ndi ochepa,chifukwa mtengo wa mayeso ndi chofunika odziwa, ophunzitsidwaogwira ntchito zaumisiri kuti achite kuyesa kuletsa ntchito yawo.

Palinso kuyezetsa magazi komwe kulipo malonda komwe kumagwiritsidwa ntchito pozindikira MtunduMa antibodies enieni a HSV, koma kuyesa kwa serological sikungathe kuzindikira choyambiriramatenda kotero angagwiritsidwe ntchito poletsa matenda obweranso.Mayeso a antigen awa amatha kusiyanitsa matenda ena am'mimba ndi malisecheherpes, monga chindoko ndi chancroid, kuthandiza matenda oyambirira ndi mankhwalamatenda a HSV.

MFUNDO
HSV antigen Rapid Test Device idapangidwa kuti izizindikira antigen ya HSVkudzera mu kutanthauzira kowoneka kwa kukula kwa mitundu mumzere wamkati.Thenembanemba inali yosasunthika ndi anti Herpes simplex virus monoclonal antibody on
chigawo choyesera.Pakuyesa, chitsanzocho chimaloledwa kuchitapo kanthu ndi mitundumonoclonal anti-HSV antibody colored partticals conjugates, omwe anali atakutidwa kalepepala lachitsanzo la mayeso.Kusakaniza kenako kumayenda pa nembanemba ndi capillary
zochita, ndipo amalumikizana ndi reagents pa nembanemba.Ngati pali HSV yokwanirama antigen mu zitsanzo, gulu lachikuda lidzapanga pagawo loyesa la nembanemba.Kukhalapo kwa gulu lachikudali kumasonyeza zotsatira zabwino, pamene kusowa kwake kumasonyeza
zotsatira zoipa.Kuwonekera kwa gulu lachikuda pa dera lolamulira limagwira ntchito ngati akuwongolera mwadongosolo.Izi zikutanthawuza kuti chiwerengero chokwanira cha chitsanzo chawonjezeredwandipo kuwonongeka kwa membrane kumachitika.